Document Detail


Successful thrombolytic therapy using tissue-type plasminogen activator in Kawasaki disease.
MedLine Citation:
PMID:  7567665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thrombolytic therapy using tissue-type plasminogen activator was performed in a 7-month-old boy with massive mural thrombi in large coronary aneurysms due to Kawasaki disease. Magnetic resonance imaging successfully demonstrated mural thrombi in both proximal and distal coronary aneurysms and their disappearance after thrombolytic therapy. We conclude that for preventing acute myocardial infarction and sudden death intravenous and intracoronary thrombolytic therapy with tissue-type plasminogen activator may help in infants and children with Kawasaki disease who have thrombi in coronary aneurysms.
Authors:
S Tsubata; F Ichida; Y Hamamichi; A Miyazaki; I Hashimoto; T Okada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  16     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1995 Jul-Aug
Date Detail:
Created Date:  1995-11-22     Completed Date:  1995-11-22     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  186-9     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Toyama Medical and Pharmaceutical University, Toyama City, Japan.
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MeSH Terms
Descriptor/Qualifier:
Coronary Aneurysm / complications,  diagnosis,  drug therapy*
Coronary Angiography
Heart Diseases / complications,  diagnosis,  drug therapy*
Humans
Infant
Magnetic Resonance Angiography
Male
Mucocutaneous Lymph Node Syndrome / complications*
Myocardial Ischemia / diagnosis,  prevention & control
Plasminogen Activators / therapeutic use*
Thrombolytic Therapy*
Thrombosis / complications,  diagnosis,  drug therapy*
Tissue Plasminogen Activator / therapeutic use*
Chemical
Reg. No./Substance:
EC 3.4.21.-/Plasminogen Activators; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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