Document Detail

Successful thrombolysis of right atrial and ventricle thrombi encircling a temporary pacemaker lead in a patient with heparin-induced thrombocytopenia type II.
MedLine Citation:
PMID:  10234725     Owner:  NLM     Status:  MEDLINE    
Only few reports exist addressing the problem of temporary pacemaker leads associated with thromboembolic disease. We report the case of a 67-year-old patient who required a temporary transfemoral pacemaker due to AV block grade III. The patient developed extensive right atrial and ventricle thrombus formation attached to the pacing wire, as well as venous thrombosis at the insertion site due to heparin-induced thrombocytopenia type II (HIT type II). After short-term thrombolysis with 1 mg rt-PA/kg b.w. complete resolution of all clots could be shown by B-mode sonography and transthoracic, as well as transesophageal echocardiography.
U Janssens; O A Breithardt; A Greinacher
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  22     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-06-18     Completed Date:  1999-06-18     Revised Date:  2005-05-12    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  678-81     Citation Subset:  IM    
Medical Clinic I, University of RWTH Aachen, Germany.
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MeSH Terms
Anticoagulants / administration & dosage,  adverse effects*,  therapeutic use
Chondroitin Sulfates / administration & dosage,  therapeutic use
Dermatan Sulfate / administration & dosage,  therapeutic use
Drug Combinations
Fibrinolytic Agents / therapeutic use*
Heart Atria
Heart Diseases / drug therapy*
Heart Ventricles
Heparin / adverse effects*
Heparinoids / administration & dosage,  therapeutic use
Heparitin Sulfate / administration & dosage,  therapeutic use
Hirudin Therapy
Hirudins / administration & dosage
Pacemaker, Artificial*
Thrombocytopenia / chemically induced*,  classification
Thrombolytic Therapy*
Thrombosis / drug therapy*
Tissue Plasminogen Activator / therapeutic use*
Reg. No./Substance:
0/Anticoagulants; 0/Drug Combinations; 0/Fibrinolytic Agents; 0/Heparinoids; 0/Hirudins; 24967-94-0/Dermatan Sulfate; 83513-48-8/danaproid; 9005-49-6/Heparin; 9007-28-7/Chondroitin Sulfates; 9050-30-0/Heparitin Sulfate; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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