Document Detail

Successful thrombolysis after pulmonary endarterectomy.
MedLine Citation:
PMID:  21095367     Owner:  NLM     Status:  MEDLINE    
We report the case of a 51-year-old woman who underwent pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. On postoperative day 1 she developed bilateral pulmonary thrombosis due to preoperatively undiagnosed heparin-induced thrombocytopenia. Systemic thrombolytic therapy with alteplase on postoperative days 5 and 6 resulted in marked clinical improvement. To our knowledge this is the first report of successful thrombolysis of pulmonary thrombosis due to heparin-induced thrombocytopenia after pulmonary endarterectomy.
Kathrin I Schmidt; Peter Fries; Susanne K Feldner; Hans-Joachim Schäfers
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  90     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2051-3     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Thoracic and Cardiovascular Surgery, University Hospital of Saarland, Homburg/Saar, Germany.
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MeSH Terms
Chronic Disease
Endarterectomy / methods*
Fibrinolytic Agents / therapeutic use*
Follow-Up Studies
Middle Aged
Pulmonary Embolism / drug therapy,  physiopathology,  surgery*
Pulmonary Wedge Pressure
Thrombolytic Therapy / methods*
Vascular Resistance
Reg. No./Substance:
0/Fibrinolytic Agents

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