| Successful therapy with hemoperfusion and plasma exchange in acute 1,2,3-trichloropropane poisoning. | |
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MedLine Citation:
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PMID: 22045893 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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1,2,3-trichloropropane (1,2,3-TCP) is commonly used as an intermediate in pesticide and an industrial specialty solvent. Acute 1,2,3-TCP poisoning is rare but a medical emergency. Sporadic cases of toxic hepatic injury from 1,2,3-TCP in humans have been reported. Liver is a target organ for 1,2,3-TCP toxicity, which may ensue in a short period after ingestion. A specific antidote against 1,2,3-TCP is not available. So it is important to distinguish that a patient with 1,2,3-TCP poisoning constitutes a medical emergency. In this case study, the poisoned patient's clinical condition and laboratory values improved gradually after she received hemoperfusion (HP) and plasma exchange, which indicated that the therapy with HP and plasma exchange were helpful in the treatment of 1,2,3-TCP poisoning. |
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Authors:
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Peng Liu; Yu-Guang Liang; Qing-Yi Meng; Cheng-Gang Zhang; Hao-Chun Wang; Xi-Gang Zhang; Guang Li; Yue-Zhong He |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-1 |
Journal Detail:
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Title: Human & experimental toxicology Volume: - ISSN: 1477-0903 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9004560 Medline TA: Hum Exp Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Affiliated Hospital of Academy of Military Medical Sciences, China and Chinese PLA General Hospital, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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