| Successful therapeutic use of rituximab in refractory membranous glomerulonephritis. | |
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MedLine Citation:
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PMID: 16878436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present the case of a 57-year-old man with nephrotic syndrome secondary to idiopathic membranous glomerulonephritis unsuccessfully treated with angiotensin-converting enzyme inhibitor (ACEI), angiotensin II receptor antagonist (ARA), prednisone and chlorambucil. After treatment with rituximab, we observed a progressive decrease of proteinuria and normalization of serum albumin. 18 months after treatment, he remained in remission. No adverse reactions to rituximab were noted throughout follow-up. |
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Authors:
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M Cobo; D Hernández; C Rodriguez; L Pérez-Tamajón |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 66 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2006 Jul |
Date Detail:
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Created Date: 2006-08-01 Completed Date: 2006-11-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 54-7 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Hospital Universitario de Canarias, Tenerife, The Canary Islands, Spain. macobo@comtf.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal
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therapeutic use* Antigens, CD20 / metabolism B-Lymphocytes / immunology Glomerulonephritis, Membranous / blood, immunology, therapy* Humans Immunologic Factors / therapeutic use* Male Middle Aged Nephrotic Syndrome / blood, immunology, therapy Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antigens, CD20; 0/Immunologic Factors; 0/rituximab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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