Document Detail

Successful reversal of bupivacaine and lidocaine-induced severe junctional bradycardia by lipid emulsion following infraclavicular brachial plexus block in a uremic patient.
MedLine Citation:
PMID:  21729815     Owner:  NLM     Status:  In-Data-Review    
Cardiac toxicity of bupivacaine has long been documented and it could be potentiated in certain circumstances, such as preexisting cardiac conduction abnormality or uremic status. The concept that lipid emulsion acts as a rescue of bupivacaine's toxicity has prevailed pending universal recognition. Herein, we report the successful use of lipid to resuscitate a female uremic patient who sustained junctional bradycardia while she was receiving ultrasound-guided infraclavicular brachial plexus block with the dose of local anesthetics far below the currently recommended maximum one. The possible mechanisms for the occurrence of cardiotoxicity in this case are discussed and the role of lipid emulsion as a treatment is reviewed.
Yu-Hsuan Shih; Chen-Hsiu Chen; Ying-Ming Wang; Kang Liu
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Publication Detail:
Type:  Journal Article     Date:  2011-06-23
Journal Detail:
Title:  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists     Volume:  49     ISSN:  1875-452X     ISO Abbreviation:  Acta Anaesthesiol Taiwan     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-07-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101214918     Medline TA:  Acta Anaesthesiol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  72-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
Department of Anesthesiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.
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