| Successful pregnancy in a woman with a human seminal plasma allergy. A case report. | |
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MedLine Citation:
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PMID: 10319315 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Human seminal plasma allergy is an anaphylaxis caused by immediate hypersensitivity to human seminal plasma. The utilization of a condom is usually recommended as the primary means of preventing an allergic reaction. Infertility resulting from condom use, however, is an undesirable complication in many cases. Here we report on a successfully established pregnancy in a woman with seminal plasma allergy. CASE: A 29-year-old, married nulligravida with a human seminal plasma allergy consulted us to conceive. She showed a positive reaction to a skin-prick test with whole semen. In order to remove the seminal plasma, the sperm were washed three times using a continuous-step density gradient centrifugation method. Artificial insemination with the washed sperm was performed without anaphylactic symptoms. After six inseminations, pregnancy was achieved, and a healthy infant was delivered. CONCLUSION: Artificial insemination with sperm devoid of seminal plasma was very useful for establishing pregnancy in a woman with a human seminal plasma allergy. |
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Authors:
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K Iwahashi; T Miyazaki; N Kuji; Y Yoshimura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 44 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-06-29 Completed Date: 1999-06-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 391-3 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaphylaxis / diagnosis, etiology*, immunology, prevention & control* Condoms Female Humans Insemination, Artificial, Homologous* / methods Pregnancy Pregnancy Outcome* Semen / immunology* Skin Tests |
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