Document Detail

Successful pregnancy in a patient with familial sea-blue histiocyte syndrome.
MedLine Citation:
PMID:  11221166     Owner:  NLM     Status:  MEDLINE    
A 27-year-old Indian woman at 23 weeks' gestation presented with decompensated liver cirrhosis, coagulopathy, restrictive lung disease with cor pulmonale and preeclampsia. She was diagnosed to have sea-blue histiocyte syndrome (SBHS) at the age of 13 years and was treated conservatively. There was worsening liver, respiratory and bone marrow function as the pregnancy progressed. She underwent a successful pregnancy despite her poor medical condition and advanced disease state. We described the first case of familial SBHS in a pregnant patient from Asia.
S A Fadilah; N R Mazeni; S K Cheong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  55     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-26     Completed Date:  2001-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  Malaysia    
Other Details:
Languages:  eng     Pagination:  510-2     Citation Subset:  IM    
Department of Haematology and Transplantation, MAKNA-HUKM Cancer Institute, Hospital Universiti Kebangsaan Malaysia (HUKM), Jalan Yaacob Latif, Cheras, 56000 Kuala Lumpur.
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MeSH Terms
Histiocytes / pathology
Infant, Newborn
Pregnancy Complications*
Pregnancy Outcome
Sea-Blue Histiocyte Syndrome / genetics*,  pathology
Spleen / pathology

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