Document Detail

Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis.
MedLine Citation:
PMID:  11174031     Owner:  NLM     Status:  MEDLINE    
Pregnancies in women suffering from advanced chronic renal failure are frequently associated with deterioration of maternal renal function, premature births and low birth weights. Prophylactic dialysis is sometimes instituted since this intervention ameliorates the uremic milieu and improves maternal status and fetal uterine environment. This report describes a successful pregnancy and delivery in a hypertensive woman with advanced chronic renal failure due to polycystic kidney disease without accelerating the natural deterioration of renal function and without instituting prophylactic dialysis. The infant was delivered at full term with a normal birth weight. Thirty months after delivery, growth and development of the child were normal and the rate of deterioration of maternal renal function, assessed by 1/creatinine, was unaffected by pregnancy. Conservative management and effective control of blood pressure may be sufficient to achieve successful pregnancy outcome when women with advanced chronic renal failure become pregnant.
K Hassan; I Weissmam; S Osman; R Gery; M Oettinger; S M Shasha; B Kristal
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nephron     Volume:  87     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-04-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Nephrology and Hypertension Unit, Western Galilee Hospital, Nahariya 22100, Israel.
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MeSH Terms
Antihypertensive Agents / administration & dosage
Hydralazine / administration & dosage
Hypertension, Renal / drug therapy
Kidney Failure, Acute / prevention & control*,  therapy
Polycystic Kidney Diseases / therapy*
Pregnancy Complications / prevention & control*,  therapy
Pregnancy Outcome*
Renal Dialysis*
Reg. No./Substance:
0/Antihypertensive Agents; 86-54-4/Hydralazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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