Document Detail


Successful pregnancy in a 63-year-old woman.
MedLine Citation:
PMID:  9130906     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To report the occurrence of an unusual case of successful pregnancy achieved by oocyte donation in a woman > 60 years of age. DESIGN: Case report. SETTING: University-based assisted reproductive technology program. PATIENT(S): Sixty-three-year old nulligravida, married for 16 years to her 60-year-old husband. Throughout her infertility treatment, the patient was believed to be 10 years younger, as she claimed. She revealed her true age of 63 only upon being referred for obstetric care at 13 weeks of gestational age. INTERVENTION(S): Oocyte donation, IVF, embryo cryopreservation, and ET. MAIN OUTCOME MEASURE(S): Attainment of pregnancy and subsequent delivery. RESULT(S): The patient underwent two cycles of oocyte donation. During the second attempt, the fresh transfer resulted in a clinical miscarriage at approximately 8 weeks of gestational age. A subsequent transfer of three frozen-thawed embryos resulted in an ongoing singleton gestation. The pregnancy was complicated by gestational diabetes (controlled by diet) and mild pregnancy-induced hypertension. Delivery by cesarean section at 38 weeks of gestational age resulted in the birth of a healthy female infant weighing 2,844 g with Apgar scores of 9 and 9. CONCLUSION(S): This case demonstrates that the uterus is capable of supporting nidation and subsequent gestation for many years beyond natural menopause. It shows that other aspects of human physiology are capable of adapting to the stresses and changes of pregnancy sufficiently well to achieve a normal birth at the age of 63 years. This case also exemplifies the difficulty in attempting to regulate the age of recipients in oocyte donation. As in other aspects of human life, when age limits are applied to the provision of certain services, human beings whose age falls outside of these limits become motivated to deceive the providers of those services to avail themselves of the services.
Authors:
R J Paulson; M H Thornton; M M Francis; H S Salvador
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  67     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-05-15     Completed Date:  1997-05-15     Revised Date:  2004-11-18    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  949-51     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, USA.
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MeSH Terms
Descriptor/Qualifier:
Breast Feeding
Cesarean Section
Diabetes, Gestational / diet therapy
Embryo Transfer
Female
Humans
Hypertension
Maternal Age*
Menopause*
Middle Aged
Oocyte Donation*
Pregnancy*
Pregnancy Complications / therapy
Pregnancy Outcome
Pregnancy, High-Risk*
Comments/Corrections
Comment In:
Fertil Steril. 1997 Dec;68(6):1153; author reply 1154-5   [PMID:  9418718 ]
Fertil Steril. 1997 Dec;68(6):1153-4   [PMID:  9418719 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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