| Successful pregnancy after fertility-sparing local resection and uterine reconstruction for low-grade endometrial stromal sarcoma. | |
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MedLine Citation:
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PMID: 22825274 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: : Fertility-sparing management of endometrial stromal sarcoma has been demonstrated, but reports of pregnancy after such management are rare in our current body of literature. CASE: : A 16-year-old nulligravid adolescent girl presented with symptoms of menometrorrhagia and was found to have a 17-cm uterine mass. The patient underwent local resection of the mass with uterine reconstruction. Pathology revealed a low-grade endometrial stromal sarcoma. She was placed on high-dose daily megestrol acetate therapy and remained disease-free for 8 years before achieving pregnancy spontaneously. The patient underwent an uncomplicated pregnancy until 34 weeks of gestation, when she presented in preterm labor and underwent cesarean delivery of a liveborn male neonate, with no evidence of disease recurrence. CONCLUSION: : Fertility-sparing management and close follow-up of low-grade endometrial stromal sarcoma may be a viable option for those desiring future fertility. |
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Authors:
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Abigail A Delaney; Ashley L Gubbels; Steve Remmenga; Paul Tomich; Kelly Molpus |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 120 ISSN: 1873-233X ISO Abbreviation: Obstet Gynecol Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-07-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 486-9 Citation Subset: AIM; IM |
Affiliation:
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From the Department of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, Nebraska; and the Halifax Health Center for Oncology, Daytona Beach, Florida. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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