Document Detail


Successful pregnancies in dialysis patients including those suffering from cystinosis and familial Mediterranean fever.
MedLine Citation:
PMID:  17136701     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For women on maintenance dialysis, pregnancy is still uncommon. The outcome of such pregnancies has improved in recent case series. Here, we report in detail the treatment of five successful pregnancies in dialysis patients from our centre. The present case series also includes the first successful pregnancy of a dialysis patient with underlying familial Mediterranean fever, and of a dialysis patient with cystinosis. We treated all patients with an intensified hemodiafiltration protocol, increased erythropoietin dosages, a generous application of water-soluble vitamins and trace elements in addition to a multidisciplinary clinical management approach with a very low threshold for hospital admission. Specifically, we report treatment of arterial hypertension with respect to changes in dry weight and pharmacological therapy. Mean gestational age at delivery was 32.8+/-3.3 weeks and mean birth weight was 1,765+/-554 g. All mothers and newborns were discharged healthy and in good condition. These modified management guidelines have led to a favourable outcome in all our patients including two patients with familial Mediterranean fever and with cystinosis, and may help to guide therapy in other pregnant dialysis patients.
Authors:
Michael Haase; Stanislao Morgera; Christian Bamberg; Horst Halle; Sebastian Martini; Duska Dragun; Hans-H Neumayer; Klemens Budde
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of nephrology     Volume:  19     ISSN:  1121-8428     ISO Abbreviation:  J. Nephrol.     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-11-30     Completed Date:  2008-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  677-81     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Charité University Medicine, Berlin-Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Birth Weight
Cystinosis / therapy*
Erythropoietin / administration & dosage*
Familial Mediterranean Fever / therapy*
Female
Gestational Age
Hemodiafiltration*
Humans
Live Birth*
Pregnancy
Trace Elements / administration & dosage*
Vitamins / administration & dosage*
Chemical
Reg. No./Substance:
0/Trace Elements; 0/Vitamins; 11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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