Document Detail


Successful perinatal outcome in an early onset intrahepatic cholestasis of pregnancy with extremely high serum hepatic function tests.
MedLine Citation:
PMID:  19499412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of a 21-year-old pregnant woman with an early onset of intrahepatic cholestasis of pregnancy with very high aminotransferases activity and bilirubin concentration. Viral and autoimmune hepatitis, and other possible causes of liver function impairment were excluded. Treatment with ursodeoxycholic acid improved biochemical markers. The patient delivered a healthy female neonate by caesarean section. Neonatal and postoperative courses were uneventful.
Authors:
Roman Smolarczyk; Monika Grymowicz; Jacek Sienko; Krzysztof Czajkowski
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  25     ISSN:  1473-0766     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-11-11     Completed Date:  2010-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  475-6     Citation Subset:  IM    
Affiliation:
Second Department of Obstetrics and Gynecology, Warsaw Medical University, Warsaw 00-315, Poland.
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MeSH Terms
Descriptor/Qualifier:
Alanine Transaminase / blood
Alkaline Phosphatase / blood
Aspartate Aminotransferases / blood
Bilirubin / blood
Cholestasis, Intrahepatic / etiology*,  metabolism*
Female
Humans
Infant, Newborn
Liver Function Tests
Pregnancy
Pregnancy Complications / metabolism*
Pregnancy Outcome*
Severity of Illness Index
Young Adult
Chemical
Reg. No./Substance:
635-65-4/Bilirubin; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase; EC 3.1.3.1/Alkaline Phosphatase

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