| Successful operation for mitral regurgitation in a patient with Gilbert's syndrome. | |
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MedLine Citation:
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PMID: 21547629 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 72-year-old woman complaining of dyspnea on effort was diagnosed as having mitral regurgitation (MR). Asymptomatic jaundice had initially been noticed during primary school, and an examination had shown hyperbilirubinemia. After the diagnosis of constitutional jaundice, she had remained well without further examination or medical treatment. Laboratory data showed a total serum bilirubin (TB) level of 12.2 mg/dl and a direct bilirubin level of 0.6 mg/dl. Transesophageal echocardiography showed severe MR, and we replaced the mitral valve. Postoperatively, genetic analyses identified constitutional jaundice as Gilbert's syndrome with Y486D mutation. The TB level gradually decreased. Four years after operation she is doing well with moderate hyperbilirubinemia and a TB level of 5 mg/dl. She is free from heart failure. |
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Authors:
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Hiroya Minami; Tatsuro Asada; Kunio Gan; Akitoshi Yamada; Yoshihiko Yano |
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Publication Detail:
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Type: Journal Article Date: 2011-05-06 |
Journal Detail:
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Title: General thoracic and cardiovascular surgery Volume: 59 ISSN: 1863-6713 ISO Abbreviation: Gen Thorac Cardiovasc Surg Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101303952 Medline TA: Gen Thorac Cardiovasc Surg Country: Japan |
Other Details:
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Languages: eng Pagination: 344-6 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Surgery, Miki City Hospital, 58-1 Kasa, Miki, Hyogo, 673-0402, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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