Document Detail

Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin.
MedLine Citation:
PMID:  17414408     Owner:  NLM     Status:  MEDLINE    
Treatment options for primary cutaneous aspergillosis in neonates are limited by the lack of pharmacokinetic and safety data of newer antifungal agents that are effective against Aspergillus spp. We report the successful treatment of cutaneous aspergillosis in an extremely low-birth-weight preterm infant with liposomal amphotericin B, voriconazole and micafungin, and provide pharmacokinetic profiles for voriconazole and micafungin.
Roberto P Santos; Pablo J Sánchez; Asuncion Mejias; Daniel K Benjamin; Thomas J Walsh; Sanjay Patel; Hasan S Jafri
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  26     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-06-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  364-6     Citation Subset:  IM    
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9063, USA.
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MeSH Terms
Amphotericin B / therapeutic use
Antifungal Agents / therapeutic use*
Aspergillosis / drug therapy*,  microbiology
Dermatomycoses / drug therapy*,  microbiology
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / drug therapy*,  microbiology
Lipoproteins / therapeutic use
Peptides, Cyclic / therapeutic use
Pyrimidines / therapeutic use
Treatment Outcome
Triazoles / therapeutic use
Grant Support
Reg. No./Substance:
0/Antifungal Agents; 0/Echinocandins; 0/Lipopeptides; 0/Lipoproteins; 0/Peptides, Cyclic; 0/Pyrimidines; 0/Triazoles; 0/liposomal amphotericin B; 0/micafungin; 0/voriconazole; 1397-89-3/Amphotericin B

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