Document Detail

Successful medical management of post-hysteroscopic metroplasty bleeding with intravenous estrogen therapy: a report of two cases and review of the literature.
MedLine Citation:
PMID:  19835811     Owner:  NLM     Status:  MEDLINE    
Complications from hysteroscopy are rare, but some are potentially life-threatening. Hemorrhage is one of the most common complications of hysteroscopy. In this study, we report 2 cases of post-hysteroscopic bleeding successfully treated with intravenous conjugated equine estrogen (CEE). In our case report, 2 women who were evaluated for infertility were diagnosed with intrauterine septum. After surgical resection of the septum, significant late post-hysteroscopic bleeding was seen in the fourth and eighteenth day of surgery, respectively. Both patients were successfully treated with intravenous CEE 25mg in normal saline solution 50 mL given over 20 minutes every 6 hours. These 2 cases illustrate that intravenous CEE therapy as a short-term treatment is relatively safe and can be considered as an alternative in the treatment of severe post-hysteroscopy bleeding in selected patients without risk factors. In patients with risk factors, such as previous thromboembolic disease, alternative modalities of treatment should be considered.
Bert Scoccia; Habibe Demir; Koray Elter; Antonio Scommegna
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of minimally invasive gynecology     Volume:  16     ISSN:  1553-4650     ISO Abbreviation:  -     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-10-19     Completed Date:  2009-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235322     Medline TA:  J Minim Invasive Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  639-42     Citation Subset:  IM    
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Illinois College of Medicine, Chicago, Illinois 60612-7313, USA.
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MeSH Terms
Estrogens / administration & dosage*
Estrogens, Conjugated (USP) / administration & dosage*
Hysteroscopy / adverse effects*
Infusions, Intravenous
Local Government
Postoperative Complications / drug therapy
Uterine Hemorrhage / drug therapy*,  etiology
Uterus / abnormalities
Reg. No./Substance:
0/Estrogens; 0/Estrogens, Conjugated (USP)

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