| Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus. | |
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MedLine Citation:
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PMID: 20680376 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Systemic lupus erythematosus (SLE) is one of the common autoimmune disorders that affect women during their childbearing years. Disease activity frequently increases during pregnancy and the postpartum period, representing a challenge for both the patient and the treating physician(s). We report a case of successful management of lupus nephritis flare in the first trimester. The patient developed bilateral leg edema and nephrotic-range proteinuria of 5 g/day. She was treated with steroids and tacrolimus, which resulted in the induction of remission during pregnancy. The patient reached full-term with no maternal or fetal complications. This case indicates that tacrolimus, which is convenient to use and has limited adverse effects, may represent a potential safe and effective treatment option for SLE nephritis during pregnancy. |
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Authors:
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Abdulkareem Alsuwaida |
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Publication Detail:
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Type: Journal Article Date: 2010-08-04 |
Journal Detail:
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Title: Modern rheumatology / the Japan Rheumatism Association Volume: 21 ISSN: 1439-7609 ISO Abbreviation: Mod Rheumatol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959226 Medline TA: Mod Rheumatol Country: Japan |
Other Details:
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Languages: eng Pagination: 73-5 Citation Subset: IM |
Affiliation:
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Department of Medicine, King Saud University, P.O. Box 2925, Riyadh, 11321, Saudi Arabia, alsuwaida@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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