| Successful management and perinatal outcome of pregnancy complicated with myelodysplastic syndrome. | |
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MedLine Citation:
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PMID: 11792414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnancy complicated with myelodysplastic syndrome (MDS) is rare and case management is controversial. We report six cases of MDS that were successfully managed during pregnancy including uneventful transvaginal delivery and satisfactory postpartum clinical prognosis. Two patients with MDS who became pregnant twice had normal uneventful deliveries showing no deterioration of MDS. Our findings suggest that pregnancy should be allowed to full-term in MDS patients, especially those of the refractory anemia type, but strict management should be provided before, during and after pregnancy. Pancytopenia might develop during pregnancy but the likelihood of transformation of MDS to leukemia due to pregnancy is remote. |
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Authors:
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Yuichiro Ikeda; Hideaki Masuzaki; Daisuke Nakayama; Takahiro Maeda; Khaleque Newaz Khan; Yuko Okita; Emiko Doi; Masao Tomonaga; Tadayuki Ishimaru |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Leukemia research Volume: 26 ISSN: 0145-2126 ISO Abbreviation: Leuk. Res. Publication Date: 2002 Mar |
Date Detail:
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Created Date: 2002-01-16 Completed Date: 2002-05-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7706787 Medline TA: Leuk Res Country: England |
Other Details:
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Languages: eng Pagination: 255-60 Citation Subset: IM |
Affiliation:
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Departments of Obstetrics and Gynecology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. ikebon@net.nagasaki-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia / genetics, pathology, therapy Anemia, Refractory, with Excess of Blasts / genetics, therapy Bone Marrow / pathology Delivery, Obstetric Diagnosis, Differential Female Follow-Up Studies Humans Infant, Newborn Karyotyping Myelodysplastic Syndromes / genetics, pathology, therapy* Pregnancy Pregnancy Complications / pathology, therapy* Pregnancy Outcome* Prognosis Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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