Document Detail

Successful full-term pregnancy in a woman with Cogan's syndrome: a case report.
MedLine Citation:
PMID:  17574494     Owner:  NLM     Status:  MEDLINE    
Cogan's syndrome (CS) is a chronic inflammatory disorder that most commonly affects young adults. Major clinical features are interstitial keratitis and vestibuloauditory dysfunction. Associations between CS and systemic vasculitis as well as aortitis also exist. The present report is the first case in the literature of pregnancy associated with Cogan syndrome, which posed a therapeutic challenge. There was a relapse of the ocular symptoms only during the first trimester of pregnancy, but the pregnancy was otherwise uneventful. The relevant literature is reviewed both with regard to the relationship of CS to pregnancy and the therapeutic approach in this situation.
Aikaterini Deliveliotou; Theodore Moustakarias; John Argeitis; George Vaggos; Nikolaos Vitoratos; Dimitrios Hassiakos
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-06-16
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-09     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  2181-3     Citation Subset:  IM    
2nd Department of Obstetrics and Gynaecology, University of Athens Medical School, Aretaieion Hospital, 76, Vas. Sofias Avenue, 11528, Athens, Greece.
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MeSH Terms
Administration, Oral
Diagnosis, Differential
Follow-Up Studies
Hearing Loss, Sensorineural / complications,  diagnosis*,  drug therapy
Infant, Newborn
Keratitis / complications,  diagnosis*,  drug therapy
Ophthalmic Solutions
Prednisolone / administration & dosage
Prednisone / administration & dosage
Pregnancy Complications*
Pregnancy Outcome
Reg. No./Substance:
0/Ophthalmic Solutions; 50-24-8/Prednisolone; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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