Document Detail

Successful fertility management of a patient with factor V deficiency: planned transfusion of fresh frozen plasma under infertility treatment.
MedLine Citation:
PMID:  21292261     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To report the case of a patient with factor V deficiency who achieved pregnancy with the planned transfusion of fresh frozen plasma (FFP) while monitoring follicle development and ovulation induction using gonadotropin. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 28-year-old nulliparous female. INTERVENTION(S): Medical management including infertility treatment. MAIN OUTCOME MEASURE(S): Clinical follow-up. RESULT(S): A patient with factor V deficiency experienced repeated ovulation-related hemoperitoneum following the withdrawal of oral contraceptive pills. The monitoring of follicle development and ovulation induction using gonadotropin followed by FFP transfusion was useful to avoid hemoperitoneum. Pregnancy was achieved within a relatively short period using intrauterine insemination. CONCLUSION(S): Planned prophylactic FFP administration and intervention with infertility treatment might be useful to minimize the risk of ovulation-related hemoperitoneum in patients with factor V deficiency.
Akira Iwase; Maki Goto; Shuichi Manabe; Wakana Hirokawa; Hiroharu Kobayashi; Tatsuo Nakahara; Sachiko Takikawa; Tomomi Kotani; Seiji Sumigama; Hiroyuki Tsuda; Takayuki Nakayama; Nobuaki Suzuki; Tadashi Matsushita; Fumitaka Kikkawa
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-2
Journal Detail:
Title:  Fertility and sterility     Volume:  -     ISSN:  1556-5653     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan; Department of Maternal and Perinatal Medicine, Nagoya University Hospital, Nagoya, Japan.
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