| Successful erythropoietin treatment for severe anemia in nephrotic syndrome without renal dysfunction. | |
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MedLine Citation:
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PMID: 8938689 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 62-year-old woman presented with nephrotic syndrome and severe anemia although the renal function was not impaired. Renal biopsy revealed the histology of membranoproliferative glomerulonephritis, and the proteinuria was resistant to steroid therapy. Iron deficiency, bleeding and other causes of anemia were ruled out, however, her serum erythropoietin level was inappropriately low. The anemia was rapidly corrected by administration of recombinant human erythropoietin. It is suggested that inappropriately low erythropoietin level, in part at least, accounts for the anemia in nephrotic syndrome. It is proposed that erythropoietin therapy should be taken into consideration for severe anemia in nephrotic syndrome even when the renal function is not impaired. |
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Authors:
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T Ishimitsu; H Ono; M Sugiyama; H Asakawa; K Oka; A Numabe; M Abe; H Matsuoka; S Yagi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Nephron Volume: 74 ISSN: 0028-2766 ISO Abbreviation: Nephron Publication Date: 1996 |
Date Detail:
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Created Date: 1997-02-20 Completed Date: 1997-02-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331777 Medline TA: Nephron Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 607-10 Citation Subset: IM |
Affiliation:
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Department of Medicine, Dokkyo University School of Medicine, Tochigi, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia
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drug therapy*,
etiology* Erythropoietin / therapeutic use* Female Humans Kidney / physiology* Middle Aged Nephrotic Syndrome / complications* |
| Chemical | |
Reg. No./Substance:
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11096-26-7/Erythropoietin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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