| Successful emergent angioplasty of neurosarcoid vasculitis presenting with strokes. | |
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MedLine Citation:
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PMID: 17015122 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Sarcoidosis is a systemic disease with neurologic involvement in approximately 5% of cases. Ischemic events related to neurosarcoid vasculitis are rare. We report the successful treatment of symptomatic neurosarcoid vasculitis with angioplasty. CASE DESCRIPTION: A 41-year-old African American with a diagnosis of neurosarcoid presented with aphasia and right-sided weakness. He was treated medically with antiplatelet agents, heparinization, and hypertensive therapy. Despite this treatment, he experienced clinical worsening and radiographic extension of his infarcts. He underwent successful angioplasty of a severe focal stenosis of the left middle cerebral artery. After the procedure, he experienced marked improvement in his symptoms and at follow-up continues to improve. CONCLUSIONS: We report the angiographic demonstration of neurosarcoidosis with large vessel changes and resultant strokes and its successful treatment with balloon angioplasty. |
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Authors:
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Jonathan L Brisman; Archana Hinduja; James S McKinney; Brian Gerhardstein |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Surgical neurology Volume: 66 ISSN: 0090-3019 ISO Abbreviation: Surg Neurol Publication Date: 2006 Oct |
Date Detail:
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Created Date: 2006-10-03 Completed Date: 2006-11-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0367070 Medline TA: Surg Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 402-4 Citation Subset: IM |
Affiliation:
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Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ 08818, USA. jbrisman@solarishs.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angioplasty, Balloon / instrumentation, methods*, trends Anterior Cerebral Artery / pathology, radiography, surgery Anticoagulants / therapeutic use Antihypertensive Agents / therapeutic use Aphasia / etiology, physiopathology, surgery Basilar Artery / pathology, radiography, surgery Brain / blood supply, pathology, physiopathology Cerebral Angiography Disease Progression Humans Magnetic Resonance Imaging Male Middle Cerebral Artery / pathology, radiography, surgery Paresis / etiology, physiopathology, surgery Sarcoidosis / complications*, physiopathology Stroke / etiology*, physiopathology, surgery* Treatment Outcome Vasculitis, Central Nervous System / etiology*, physiopathology, surgery* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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