| Successful conservative treatment of endometrial carcinoma permitting subsequent pregnancy: report of two cases. | |
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MedLine Citation:
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PMID: 10843466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two women with endometrial carcinoma who wished to preserve their childbearing ability received conservative treatment by medroxyprogesterone acetate (MPA, 600 mg/day for 22 weeks and 29 weeks, respectively). Following regression of endometrial lesions, their infertility was treated by inducing ovulation. Intact pregnancy was diagnosed 13 months and 11 months after completion of the MPA treatment, respectively. One patient had a twin pregnancy and delivered two infants at 35 weeks of gestational age. The other patient delivered a full-term baby. They had no evidence of recurrence 60 months and 31 months after the conservative treatment, respectively. We believe this conservative treatment with progestin may be safely performed for young patients with endometrial cancer who wish to preserve their fertility. |
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Authors:
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T Jobo; M Imai; M Kawaguchi; M Kenmochi; H Kuramoto |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of gynaecological oncology Volume: 21 ISSN: 0392-2936 ISO Abbreviation: Eur. J. Gynaecol. Oncol. Publication Date: 2000 |
Date Detail:
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Created Date: 2000-09-26 Completed Date: 2000-09-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8100357 Medline TA: Eur J Gynaecol Oncol Country: ITALY |
Other Details:
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Languages: eng Pagination: 119-22 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, School of Medicine, Kitasato University, Kanagawa, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
/
diagnosis,
drug therapy*,
pathology* Adult Drug Administration Schedule Endometrial Neoplasms / diagnosis, drug therapy*, pathology* Female Follow-Up Studies Humans Medroxyprogesterone / administration & dosage* Pregnancy* Progesterone Congeners / administration & dosage* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Progesterone Congeners; 520-85-4/Medroxyprogesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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