Document Detail

Successful combination therapy of a proximal haemophilic pseudotumour with surgery, radiation and embolization in a child with mild haemophilia A.
MedLine Citation:
PMID:  17286777     Owner:  NLM     Status:  MEDLINE    
We describe the management of a young boy with mild haemophilia A and a massive iliac pseudotumour with a multi modality approach involving factor replacement, radiation therapy, embolization and surgery. The patient was initially treated with recombinant factor VIII and radiation therapy. Because of inadequate response and worsening of bony erosion, the patient had a preoperative embolization followed by surgical excision. The surgical procedure was associated with minimal blood loss and the patient had a relatively smooth postoperative course with no physical morbidity. This case illustrates successful aggressive management of a large, proximally located pelvic pseudotumour, which resulted in an excellent outcome despite the need for a normally morbid operation.
S P Ahuja; R Sidonio; A B Raj; S J Bertolone; C Silverman; D P Antekeier; M E Fallat
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Haemophilia : the official journal of the World Federation of Hemophilia     Volume:  13     ISSN:  1351-8216     ISO Abbreviation:  Haemophilia     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-08     Completed Date:  2007-08-23     Revised Date:  2009-10-21    
Medline Journal Info:
Nlm Unique ID:  9442916     Medline TA:  Haemophilia     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA.
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MeSH Terms
Bone Diseases / therapy*
Combined Modality Therapy / methods
Embolization, Therapeutic / methods
Factor VIII / therapeutic use
Granuloma, Plasma Cell / therapy*
Hemophilia A / complications*
Tomography, X-Ray Computed
Reg. No./Substance:
9001-27-8/Factor VIII

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