| Successful closure of the patent ductus arteriosus by indomethacin in an extremely low birth weight infant of very advanced postnatal age. | |
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MedLine Citation:
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PMID: 9568226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Many studies demonstrate the efficacy of closure of a patent ductus arteriosus with indomethacin, but also show that success diminishes markedly with increasing postnatal age. For this reason surgical ligation is usually preferred after the first month of life. We describe the case of a male premature infant (25 weeks gestation, birth weight 680 g), in whom a PDA was successfully closed with indomethacin (0.1 mg/kg once daily intravenously for 6 days) at the age of 11 weeks. Thus it may be concluded that closure by drug may be attempted before surgical ligation even in cases of advanced postnatal age. |
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Authors:
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W Sterniste; C Gabriel; M Sacher |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric cardiology Volume: 19 ISSN: 0172-0643 ISO Abbreviation: Pediatr Cardiol Publication Date: 1998 May-Jun |
Date Detail:
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Created Date: 1998-05-21 Completed Date: 1998-05-21 Revised Date: 2008-02-20 |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 256-8 Citation Subset: IM |
Affiliation:
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Pediatric Department, Danube Hospital, Vienna, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cyclooxygenase Inhibitors
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therapeutic use* Ductus Arteriosus, Patent / drug therapy* Humans Indomethacin / therapeutic use* Infant Infant, Very Low Birth Weight* Injections, Intravenous Male |
| Chemical | |
Reg. No./Substance:
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0/Cyclooxygenase Inhibitors; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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