Document Detail

Successful two-stage correction of ventricular septal defect and patent ductus arteriosus in a patient with fixed pulmonary hypertension.
MedLine Citation:
PMID:  19812882     Owner:  NLM     Status:  MEDLINE    
We report a case of a 6-year-old boy with fixed severe pulmonary artery hypertension secondary to a ventricular septal defect (VSD) together with a patent ductus arteriosus (PDA). As a preliminary step, PDA embolization was performed following therapy with inhaled prostacyclin over a period of 6 months. Further, the patient underwent successful surgical VSD closure. We postulate that a staged procedure with long-term prostaglandin therapy might be capable of reducing pulmonary artery resistance and permitting total correction in a patient once considered to have inoperable pulmonary arteriopathy.
Aysenur Pac; Tugcin Bora Polat; Kerem Vural; Mustafa Pac
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-08
Journal Detail:
Title:  Pediatric cardiology     Volume:  31     ISSN:  1432-1971     ISO Abbreviation:  Pediatr Cardiol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-04-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-3     Citation Subset:  IM    
Department of Pediatric Cardiology, Turkiye Yuksek Ihtisas Education and Research Hospital, Kizilay S, No: 4, 06100 Sihhiye, Ankara, Turkey.
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MeSH Terms
Administration, Inhalation
Combined Modality Therapy
Ductus Arteriosus, Patent / therapy*
Embolization, Therapeutic*
Heart Septal Defects, Ventricular / surgery*
Hypertension, Pulmonary / therapy*
Iloprost / administration & dosage*
Septal Occluder Device
Vasodilator Agents / administration & dosage*
Reg. No./Substance:
0/Vasodilator Agents; 78919-13-8/Iloprost

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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