| Successful treatment of dwarfism secondary to long-term steroid therapy in steroid-dependent nephrotic syndrome. | |
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MedLine Citation:
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PMID: 20647659 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Prolonged steroid therapy is generally used for steroid-dependent nephrotic syndrome in pediatric patients. However, dwarfism secondary to a long-term regimen and its successful reverse is rarely reported. The underlying mechanism of dwarfism is still poorly understood, as both long-term steroid use and nephrotic syndrome may interact or independently interfere with the process of growth. Here, we present a 17-year-old patient with dwarfism and steroid-dependent nephrotic syndrome and the successful treatment by recombinant human growth factor and cyclosporine A with withdrawal of steroid. We also briefly review the current understanding and the management of dwarfism in pediatric patients with nephrotic syndrome. |
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Authors:
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Linlin Sun; Dongping Chen; Xuezhi Zhao; Chenggang Xu; Changlin Mei |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2010-07-15 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 49 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1417-21 Citation Subset: IM |
Affiliation:
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Kidney Institute of PLA, Changzheng Hospital, Second Military Medical University, China. |
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