Document Detail


Successful Management with CHOP for Pulmonary Lymphomatoid Granulomatosis in a Dog.
MedLine Citation:
PMID:  21139353     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 3-year-old, spayed female miniature dachshund was presented for vomiting and anorexia. Thoracic radiographs and CT scan revealed abnormal pulmonary opacities at bilateral caudal lobe. Cytological analysis of the pulmonary mass revealed the presence of large lymphohistiocytic cells and small lymphocytes with occasional neutrophils and plasma cells. An open lung biopsy was performed and a diagnosis of pulmonary lymphomatoid granulomatosis (LYG) was made. The dog was administered CHOP based therapy (modified UW-25), and it survived for 1,022 days after admission. Immunohistochemistry revealed pulmonary lesions consisted of many CD79a positive B cells aggregation and proliferation with prominent angiocentric pattern. This was the first case of canine pulmonary LYG managed by CHOP chemotherapy.
Authors:
Singo Hatoya; Daijiro Kumagai; Seiko Takeda; Emi Yamamoto; Masako Nakanishi; Mitsuru Kuwamura; Kikuya Sugiura; Hiroshi Sasai; Jyoji Yamate; Toshio Inaba
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Publication Detail:
Type:  Journal Article     Date:  2010-12-06
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  73     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  527-30     Citation Subset:  IM    
Affiliation:
Department of Advanced Pathobiology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University.
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