Document Detail


Successful management of peri-implantitis with a regenerative approach: a consecutive series of 51 treated implants with 3- to 7.5-year follow-up.
MedLine Citation:
PMID:  22254219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The results of a case series of 51 consecutively treated, peri-implantitis-affected implants in 38 patients with follow-up measurements from 3 to 7.5 years are presented. Each implant displayed bleeding on probing, probing depths ≥ 6 mm, and bone loss ≥ 4 mm prior to surgery. A successful regenerative approach including surface decontamination, use of enamel matrix derivative, a combination of platelet-derived growth factor with anorganic bovine bone or mineralized freeze-dried bone, and coverage with a collagen membrane or a subepithelial connective tissue graft was employed in all cases. Patients were divided into two groups. Group 1 included patients in which the greatest defect depth was visible on radiographs; group 2 included patients in which the greatest loss of bone was on the facial or oral aspect of the implant. Bone level changes in patients in group 2 were determined by probe sounding under local anesthesia. Probing depth reductions at 3 to 7.5 years of follow-up were 5.4 and 5.1 mm in groups 1 and 2, respectively. Concomitant bone level gain was 3.75 mm in group 1 and 3.0 mm in group 2. No implant in either group lost bone throughout the duration of the study. The results to date with this regenerative approach for the treatment of peri-implantitis appear to be encouraging.
Authors:
Stuart J Froum; Scott H Froum; Paul S Rosen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of periodontics & restorative dentistry     Volume:  32     ISSN:  1945-3388     ISO Abbreviation:  Int J Periodontics Restorative Dent     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-06-18     Revised Date:  2013-04-30    
Medline Journal Info:
Nlm Unique ID:  8200894     Medline TA:  Int J Periodontics Restorative Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-20     Citation Subset:  D    
Affiliation:
Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, NY, USA. dr.froum@verizon.net
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Alveolar Bone Loss / radiography,  surgery*
Bone Matrix / transplantation
Bone Regeneration / drug effects*
Bone Substitutes
Collagen
Decontamination
Dental Enamel Proteins / pharmacology*,  therapeutic use
Dental Implants / microbiology
Female
Follow-Up Studies
Guided Tissue Regeneration, Periodontal / methods*
Humans
Male
Membranes, Artificial
Middle Aged
Peri-Implantitis / surgery*
Periodontal Debridement
Periodontal Index
Platelet-Derived Growth Factor / pharmacology,  therapeutic use
Recombinant Proteins / pharmacology,  therapeutic use
Chemical
Reg. No./Substance:
0/Bone Substitutes; 0/Dental Enamel Proteins; 0/Dental Implants; 0/Membranes, Artificial; 0/Platelet-Derived Growth Factor; 0/Recombinant Proteins; 0/enamel matrix proteins; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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