| Success rate of repeated fine needle aspiration biopsy of clinically suspicious thyroid nodules. | |
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MedLine Citation:
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PMID: 22552740 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: The success rate of FNAB in clinical setting is quite low. There were several attempts made to improve the success rate of this method. It is anticipated that a double FNAB in one session would increase the success rate of FNAB. PATIENTS, METHODS: 176 consecutive patients (130 women, 46 men; mean age 56 years ± 11) with at least one clinically suspicious nodule were included in this study. Each individual nodule was biopsied twice (20G- and 21G-needle). In 33 patients, two suspicious nodules were biopsied, accounting for a total of 209 biopsied thyroid nodules. To evaluate the success rate the number of cell formations and the total number of cells in each cell formation were counted. RESULTS: The biopsy with the 20G needle provided in mean 40 cell cluster with a mean of 830 cells whereas the 21G needle provided in mean 41 cell cluster with a mean of 1010 cells. With the 20G needle the success rate was 73%, with the 21G needle 78% and the combination of the both biopsies provided a success rate of 87% (p = 0.01). Based on the number of cell formations and the total number of cells, the difference between the two needle sizes was not significant (p = 0.5 for cell formations and p = 0.9 for the total number of cells, respectively). CONCLUSION: A double FNAB of suspicious thyroid nodules in one session provides a higher success rate, and a 21G needle is sufficient enough. |
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Authors:
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J Nagarajah; J Farahati; R Görges; F Grabellus; A Bockisch; S-Y Sheu-Grabellus |
Publication Detail:
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Type: Journal Article Date: 2012-05-03 |
Journal Detail:
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Title: Nuklearmedizin. Nuclear medicine Volume: 51 ISSN: 0029-5566 ISO Abbreviation: Nuklearmedizin Publication Date: 2012 |
Date Detail:
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Created Date: 2012-08-06 Completed Date: 2013-01-18 Revised Date: 2013-04-22 |
Medline Journal Info:
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Nlm Unique ID: 7609387 Medline TA: Nuklearmedizin Country: Germany |
Other Details:
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Languages: eng Pagination: 116-8 Citation Subset: IM |
Affiliation:
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Klinik für Nuklearmedizin, Universität Duisburg-Essen, Essen, Germany. james.nagarajah@uk-essen.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Fine-Needle
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statistics & numerical data* Female Germany / epidemiology Humans Male Middle Aged Prevalence Reproducibility of Results Sensitivity and Specificity Thyroid Nodule / epidemiology*, pathology* |
| Comments/Corrections | |
Comment In:
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Nuklearmedizin. 2012;51(5):N47; author reply N47
[PMID:
23494110
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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