Document Detail

Success rate and challenges of fetal anesthesia for ultrasound guided fetal intervention by maternal opioid and benzodiazepine administration.
MedLine Citation:
PMID:  22928538     Owner:  NLM     Status:  Publisher    
Abstract Objective: The safe and effective methods of fetal anesthesia/analgesia during ultrasound guided direct fetal procedure is yet to be determined. The authors investigated whether maternal diazepam/fentanyl administration meets this purpose. Methods: The medical/anesthesia records were retrospectively reviewed in cases between 2001 to 2010 at a tertiary perinatal center. Success rate as well as maternal and fetal complications were analyzed. Results: Among the 150 procedures in 118 fetuses, diazepam 10mg and fentanyl 200μg sufficiently prevented fetal movement upon the procedure in 56% of the procedures. Supplemetal anesthetic agents such as nitrous oxide and propofol were needed in other cases. No serious maternal complication was noted, while fetal cardiac arrest/severe bradycardia was noted in 3 fetuses, one of which was successfully resuscitated by intracardiac adrenalin injection. Conclusions: Maternal diiazepam/fentanyl administration offered adequate fetal condition without significant maternal complications. Since these procedures are performed to treat severe fetal conditions, preparation for fetal resuscitation is also important.
Yuki Ohashi; Katsuo Terui; Kazumi Tamura; Motshi Tanaka; Kazunori Baba
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-29
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Anesthesiology, Kyorin University School of Medicine, Tokyo, Japan.
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