Document Detail


Subtyping and env C2/V3 sequence analysis of HIV-1 isolated from HIV-infected children hospitalized in Children Hospital 1, Vietnam during 2004-2005.
MedLine Citation:
PMID:  19380373     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
A molecular epidemiological study was conducted on 104 HIV-1 strains isolated from HIV-infected children hospitalized in Children Hospital 1 in Ho Chi Minh City, Vietnam during 2004-2005. Genetic subtyping based on env C2/V3 sequences revealed that CRF01-AE was the sole circulating recombinant form found in this study. Sequence analysis of the V3 loop showed that GPGQ tetramer was the most common V3 loop core motif identified in the HIV-1 strains studied (89.5%). The findings raise great concern about HIV-infected children in Vietnam and provide up-to-date molecular epidemiological information of HIV-1 circulating in Vietnam during the study period.
Authors:
Quang Duy Trinh; Ngan Thi Kim Pham; Bao Quoc Lam; Thoa Phan Kim Le; Khanh Huu Truong; Thinh Quoc Le; Hung Thanh Vo; Thuong Chi Tang; Tuan Manh Ha; Yasuyuki Izumi; Masashi Mizuguchi; Satoshi Hayakawa; Hiroshi Ushijima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-04-20
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  55     ISSN:  1465-3664     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  399-401     Citation Subset:  IM    
Affiliation:
Department of Developmental Medical Sciences, Institute of International Health, Graduate School of Medicine, the University of Tokyo, Japan.
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