| Subtypes of irritable bowel syndrome on Rome III criteria : a multi-center study. | |
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MedLine Citation:
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PMID: 21929652 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background and Aims: To explore the distribution and clinical characteristics of four subtypes of irritable bowel syndrome (IBS) based on Rome III criteria in Chinese. Methods: Consecutive 754 IBS outpatients from three tertiary hospitals in China were included. Diagnostic criteria were based on Rome II or Rome III. Results: Among 754 outpatients, 510(67.6%) patients met Rome II criteria, 735(97.5%) patients met Rome III criteria and 492(65.3%) patients met both criteria. Among 735 patients who met Rome III criteria, 66.3% were IBS with diarrhea (IBS-D), 14.7% were IBS with constipation (IBS-C), 4.2% were mixed IBS (IBS-M) and 14.8% were unsubtyped IBS (IBS-U). Most of IBS-D, IBS-C and IBS-M patients based on Rome III criteria matched to diarrhea-predominant IBS (D-IBS), constipation-predominant IBS (C-IBS) and alternating IBS(A-IBS) based on Rome II criteria respectively. Among IBS-U patients, 57.0%, 33.3% and 9.7% were C-IBS, D-IBS and A-IBS respectively. For IBS-M, the frequencies of bowel movements were stable in 48.4% patients and variable in 51.6% patients. Defecation urgency and straining were most frequent in IBS-M and least frequent in IBS-U patients than other subtypes. About 77.2% of IBS-U patients had abnormal stool frequency (<3/week or >3/day). Conclusion: Rome III criteria is more sensitive and practical in diagnosing IBS. IBS-D is the most frequent subtype, which is followed by IBS-U, IBS-C and IBS-M. IBS-U is a new subtype which warrants further studies. |
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Authors:
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Xin Yao; Yun Sheng Yang; Li Hong Cui; Ka Bing Zhao; Zhen Hua Zhang; Li Hua Peng; Xu Guo; Gang Sun; Jun Shang; Wei Feng Wang; Jia Feng; Qiyang Huang |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-19 |
Journal Detail:
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Title: Journal of gastroenterology and hepatology Volume: - ISSN: 1440-1746 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing , Department of Gastroenterology, Naval General Hospital, Beijing and Department of Gastroenterology, Bethune International Peace Hospital, Shijiazhuang, China. |
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