| Subtraction CT angiography for evaluation of intracranial aneurysms: comparison with conventional CT angiography. | |
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MedLine Citation:
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PMID: 19408001 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of our study was to compare the diagnostic performance of subtraction computed tomography angiography (CTA) with conventional nonsubtracted CTA and digital subtraction angiography (DSA) for the detection of intracranial aneurysms. A total of 76 patients underwent both subtraction CTA and conventional CTA for the detection and therapy planning of suspected intracranial aneurysms. Subtraction and conventional CTA images were independently assessed by two readers in a blinded manner. The possibility of endovascular treatment or surgical clipping was also assessed based on information provided by CT angiograms alone. In 64 patients, 75 aneurysms were present on DSA. On a per-aneurysm basis, the sensitivity of subtraction CTA was 98.6% for reader 1, and 100% for reader 2. However, sensitivity of conventional CTA was 94.6% for reader 1, and 93.3% for reader 2. Therapeutic decisions could be made regarding 63 patients based on information provided by subtraction CTA images. However, conventional CTA provided sufficient information to make this decision for 55 patients. Conventional CTA has limited sensitivity in detecting very small aneurysms as well as aneurysms adjacent to bone. Subtraction CTA performed on a 64-row multidetector CT is an accurate and promising diagnostic tool that seems to be equivalent to 2D DSA for the detection and pretreatment planning of intracranial aneurysms. |
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Authors:
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Qi Li; Fajin Lv; Yongmei Li; Kewei Li; Tianyou Luo; Peng Xie |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-05-01 |
Journal Detail:
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Title: European radiology Volume: 19 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-07-31 Completed Date: 2009-10-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 2261-7 Citation Subset: IM |
Affiliation:
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Department of Neurology, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angiography, Digital Subtraction / methods* Cerebral Angiography / methods* Female Humans Intracranial Aneurysm / radiography* Male Middle Aged Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / methods* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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