Document Detail

Subtotal resection of the head of the pancreas combined with ductal obliteration of the distal pancreas in chronic pancreatitis.
MedLine Citation:
PMID:  3827358     Owner:  NLM     Status:  MEDLINE    
Subtotal resection of the head of the pancreas combined with duct obliteration of the distal pancreas by prolamine was performed in 12 selected patients who had chronic alcohol-induced pancreatitis with most destruction in the proximal pancreas. The main indication for operation was intractable pain. There was no postoperative mortality but morbidity was high when no pancreaticojejunostomy was constructed. After a follow-up period of 32 months, lasting pain relief was obtained in 10 patients; pseudocyst formation occurred in three patients; calcification of the distal pancreas, absent before operation, was demonstrated in four of six patients; six of 11 nondiabetic patients became hyperglycemic either abruptly (1 patient) or progressively (5 patients); quality of life improved in most patients. This procedure preserves the stomach, duodenum, spleen, distal pancreas and common bile duct if possible. However, pancreatic ductal obliteration with prolamine does not prevent relapses of chronic pancreatitis.
R P Kerremans; F M Penninckx; J De Groote; J Fevery
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of surgery     Volume:  205     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-04-03     Completed Date:  1987-04-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  240-5     Citation Subset:  AIM; IM    
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MeSH Terms
Calcinosis / etiology
Chronic Disease
Diabetes Mellitus, Type 1 / etiology
Drug Combinations
Fatty Acids*
Follow-Up Studies
Hyperglycemia / etiology
Middle Aged
Pancreatectomy / adverse effects,  methods*,  mortality
Pancreatic Ducts
Pancreatic Pseudocyst / etiology
Pancreatitis / pathology,  physiopathology,  surgery*
Propylene Glycols*
Proteins / therapeutic use*
Quality of Life
Reg. No./Substance:
0/Drug Combinations; 0/Fatty Acids; 0/Propylene Glycols; 0/Proteins; 117-96-4/Diatrizoate; 9010-66-6/Zein; 91196-33-7/alcoholic prolamine solution

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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