| Subtle glucocorticoid excess in patients with adrenal incidentaloma. | |
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MedLine Citation:
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PMID: 1543208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Incidentally discovered adrenal tumors (incidentalomas) are fairly common since the advent of noninvasive methods of imaging the abdomen. Patients with incidentaloma usually undergo screening for overproduction of glucocorticoids by measurement of basal steroid excretion. We describe an asymptomatic patient with an incidentaloma with normal basal steroid excretion whose only manifestation of subtle steroid overproduction was the failure of steroid excretion to be suppressed normally with dexamethasone. It appears tht the more careful the search for subtle evidence of steroid overproduction in patients with incidentaloma, the more common the finding; perhaps up to 50% of patients with incidentaloma have some subtle steroid overproduction. We review the literature on this subject, and evaluate the various possible approaches of how intensively to study steroid dynamics in patients with incidentaloma. |
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Authors:
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H N Rosen; S L Swartz |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The American journal of medicine Volume: 92 ISSN: 0002-9343 ISO Abbreviation: Am. J. Med. Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-04-08 Completed Date: 1992-04-08 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 213-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Beth Israel Hospital, Boston, Massachusetts 02215. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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blood*,
surgery Adrenal Gland Neoplasms / blood*, surgery Adult Glucocorticoids / blood* Humans Male |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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