Document Detail

Subthreshold diode micropulse photocoagulation for the treatment of clinically significant diabetic macular oedema.
MedLine Citation:
PMID:  15615751     Owner:  NLM     Status:  MEDLINE    
AIM: To report the visual and clinical outcomes of a pilot study of subthreshold diode micropulse (SDM) laser photocoagulation for clinically significant diabetic macular oedema (CSMO).
METHODS: The results of infrared (810 nm) SDM laser photocoagulation for CSMO were retrospectively reviewed in 95 eyes of 69 consecutive patients with mild to moderate non-proliferative diabetic retinopathy. The same laser parameters were used for each patient. Only the number of laser applications varied between patients, depending on their macular findings. Primary outcome measures were Snellen visual acuity, fluorescein angiographic leakage, and CSMO status.
RESULTS: Visual acuity was stable or improved in 85% of treated eyes, with a mean follow up of 12.2 months (range 3-29 months). CSMO decreased in 96% and resolved in 79% of treated eyes. No adverse laser events occurred. No laser lesions were detectable ophthalmoscopically or angiographically after treatment, consistent with calculations based on ANSI Z136.1 laser safety standards suggestive of only histologically detectable tissue effects at the laser exposure levels. No laser scarring was observed during the follow up period.
CONCLUSION: Subthreshold diode micropulse laser photocoagulation minimises chorioretinal damage in the management of CSMO and demonstrates a beneficial effect on visual acuity and CSMO resolution. Prospective studies are needed to fully evaluate this technique.
J K Luttrull; D C Musch; M A Mainster
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  89     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-23     Completed Date:  2005-01-18     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  74-80     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Diabetic Retinopathy / physiopathology,  surgery*
Fluorescein Angiography / methods
Laser Coagulation / methods*
Macula Lutea / surgery*
Macular Edema / physiopathology,  surgery*
Middle Aged
Pilot Projects
Postoperative Care / methods
Postoperative Complications / etiology
Retrospective Studies
Treatment Outcome
Visual Acuity / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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