| Substrate preference in aminophylline-stimulated thermogenesis. | |
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MedLine Citation:
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PMID: 4010466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study investigated the suitability of different substrates on aminophylline (AMPY)-induced thermogenesis in rats during cold exposure. Feeding of distilled water 60 min prior to cold exposure in two-day fasted rats resulted in the lowest total heat production and final body temperature in both saline- and AMPY-treated groups. Feeding of 5 ml Intralipid (2 Kcal/ml), a triglyceride mixture, did not improve thermogenesis beyond the control levels. However, feeding of isocaloric substitutes of sucrose elevated significantly the total thermogenesis by 7.9% and 7.4% and final body temperature by 2.23 and 1.61 degrees C, respectively, in saline- and AMPY-treated groups. The increase in thermogenesis by sucrose is not due to its thermic effect. It is concluded that sucrose, in combination with AMPY, may be of value in improving resistance to cold. |
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Authors:
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L C Wang; T F Lee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Life sciences Volume: 36 ISSN: 0024-3205 ISO Abbreviation: Life Sci. Publication Date: 1985 Jul |
Date Detail:
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Created Date: 1985-08-06 Completed Date: 1985-08-06 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0375521 Medline TA: Life Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 2539-46 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aminophylline
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pharmacology* Animals Body Temperature / drug effects Body Temperature Regulation / drug effects* Cattle Cold Temperature Fat Emulsions, Intravenous / pharmacology Fatty Acids, Nonesterified / metabolism Male Muscles / metabolism Rabbits Rats Rats, Inbred Strains Sucrose / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Fat Emulsions, Intravenous; 0/Fatty Acids, Nonesterified; 317-34-0/Aminophylline; 57-50-1/Sucrose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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