Document Detail


<em>N</em>-Substituted 5-Chloro-6-phenylpyridazin-3(2<em>H</em>)-ones: Synthesis, Insecticidal Activity Against <em>Plutella xylostella </em>(L.) and SAR Study.
MedLine Citation:
PMID:  22869161     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A series of <em>N</em>-substituted 5-chloro-6-phenylpyridazin-3(2<em>H</em>)-one derivatives were synthesized based on our previous work; all compounds were characterized by spectral data and tested for <em>in vitro</em> insecticidal activity against <em>Plutella xylostella</em>. The results showed that the synthesized pyridazin-3(2<em>H</em>)-one compounds possessed good insecticidal activities, especially the compounds <strong>4b</strong>, <strong>4d</strong>, and <strong>4h </strong>which showed > 90% activity at 100 mg/L. The structure-activity relationships (SAR) for these compounds were also discussed.
Authors:
Jian Wu; Shenghong Kang; Qinkun Yuan; Lijun Luo; Juan Ma; Qingcai Shi; Song Yang
Publication Detail:
Type:  Journal Article     Date:  2012-08-06
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  17     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2012  
Date Detail:
Created Date:  2012-08-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  9413-20     Citation Subset:  IM    
Affiliation:
State Key Laboratory Breeding Base of Green Pesticides and Agricultural Bioengineering, Key Laboratory of Green Pesticides and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China. jianwu2691@yahoo.com.cn.
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