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Substantiation of an artificial saliva formulated for use in a masticatory apparatus.
MedLine Citation:
PMID:  22988786     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The aim of this work was to substantiate artificial saliva prepared for use in a masticator apparatus. Mastication's goal is to produce a viscous and plastic food bolus where these properties authorize a safe swallow. Apart from its biochemical contribution, saliva is mainly used in this kind of apparatus to provide a viscous component to the bolus. Artificial saliva was prepared with water and minerals, and completed with mucin and amylase. Different physico-chemical conditions were applied and the resultant viscosity was compared to that of human saliva. Mechanically- or chemically-stimulated salivas of ten healthy subjects were collected. Viscosity was measured with a capillary viscometer in response to changes in measurement's temperature, air exposure or pH. The effects of circadian saliva collection and the stimulation type on viscosity of human saliva were also studied. Viscosity of artificial and human salivas was comparable. An increase in the measurement's temperature or a 30 min-exposure of saliva to air led to a significant decrease in viscosity of both types of saliva. Amylase in artificial saliva did not change viscosity. The viscosity of human saliva displayed important subject variability as well as a dependence on the stimulation type of saliva production. This work allowed a useful evaluation of the formulated artificial saliva. It exhibited similar viscosity as the natural saliva in response to different methodological conditions. Therefore the proposed artificial saliva satisfies the major requirement of viscosity for a use in the masticator apparatus designed to prepare a food bolus.
Authors:
V Roger-Leroi; A Mishellany-Dutour; A Woda; M Marchand; M A Peyron
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Odonto-stomatologie tropicale = Tropical dental journal     Volume:  35     ISSN:  0251-172X     ISO Abbreviation:  Odontostomatol Trop     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8103679     Medline TA:  Odontostomatol Trop     Country:  Senegal    
Other Details:
Languages:  eng     Pagination:  5-14     Citation Subset:  D    
Affiliation:
lermont Université, Univ. d'Auvergne, EA 3847, Déficiences Incapacités et Désavantages en Santé Orale, Clermont-Ferrand, France.
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