| Substantia innominata: MR findings in Parkinson's disease. | |
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MedLine Citation:
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PMID: 15316699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To elucidate MR imaging changes of the substantia innominata in Parkinson's disease (PD), using a 1.5-T superconductive MR unit, the thickness of the substantia innominata was measured on coronal thin-section images in 44 PD patients and 20 age-matched control subjects. We also evaluated the correlation between the thickness of the substantia innominata and mental status in PD patients. Mean thickness of the substantia innominata was 2.3 mm in PD patients, and 2.5 mm in control subjects. Thinning of the substantia innominata was statistically significant in PD patients compared with control subjects, although there were large overlaps. Among the PD patients, thinning was remarkable in cases with dementia. A positive correlation between thickness of substantia innominata and score of Mini-Mental-Status-Examination was also observed in PD patients. Atrophy of the substantia innominata was demonstrated, especially in PD patients with cognitive impairment, on coronal MR images, and this is compatible with the previous pathological reports. |
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Authors:
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Hirobumi Oikawa; Makoto Sasaki; Shigeru Ehara; Takashi Abe |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuroradiology Volume: 46 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 2004 Oct |
Date Detail:
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Created Date: 2005-08-18 Completed Date: 2005-10-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: Germany |
Other Details:
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Languages: eng Pagination: 817-21 Citation Subset: IM |
Affiliation:
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Iwate Medical University, 19-1 Uchimaru, Morioka, Japan. oihiro@iwate-med.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Case-Control Studies Cognition Disorders / etiology, pathology Dementia / etiology, pathology Female Humans Magnetic Resonance Imaging Male Middle Aged Parkinson Disease / pathology*, psychology Prospective Studies Psychological Tests Severity of Illness Index Substantia Innominata / pathology* |
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