| Substandard medicines in resource-poor settings: a problem that can no longer be ignored. | |
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MedLine Citation:
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PMID: 18631318 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The circulation of substandard medicines in the developing world is a serious clinical and public health concern. Problems include under or over concentration of ingredients, contamination, poor quality ingredients, poor stability and inadequate packaging. There are multiple causes. Drugs manufactured for export are not regulated to the same standard as those for domestic use, while regulatory agencies in the less-developed world are poorly equipped to assess and address the problem. A number of recent initiatives have been established to address the problem, most notably the WHO pre-qualification programme. However, much more action is required. Donors should encourage their partners to include more explicit quality requirements in their tender mechanisms, while purchasers should insist that producers and distributors supply drugs that comply with international quality standards. Governments in rich countries should not tolerate the export of substandard pharmaceutical products to poor countries, while developing country governments should improve their ability to detect substandard medicines. |
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Authors:
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J-M Caudron; N Ford; M Henkens; C Macé; R Kiddle-Monroe; J Pinel |
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Publication Detail:
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Type: Journal Article; Review Date: 2008-07-08 |
Journal Detail:
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Title: Tropical medicine & international health : TM & IH Volume: 13 ISSN: 1365-3156 ISO Abbreviation: Trop. Med. Int. Health Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-09-04 Completed Date: 2008-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610576 Medline TA: Trop Med Int Health Country: England |
Other Details:
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Languages: eng Pagination: 1062-72 Citation Subset: IM |
Affiliation:
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Médecins Sans Frontières, Geneva, Switzerland, and AEDES Fondation, Brussels, Belgium. jean_michelcaudron@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Developing Countries Drug Contamination / legislation & jurisprudence, prevention & control* Drug Industry / legislation & jurisprudence, standards* Drug Labeling / standards* Fraud / legislation & jurisprudence, prevention & control Humans Pharmaceutical Preparations / standards* Poverty Quality Control World Health Organization |
| Chemical | |
Reg. No./Substance:
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0/Pharmaceutical Preparations |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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