Document Detail

Subplasmalemmal linear density: a mesodermal feature and a diagnostic aid.
MedLine Citation:
PMID:  7076219     Owner:  NLM     Status:  MEDLINE    
Subplasmalemmal linear density (SLD), a surface structure known to occur on mononuclear phagocytes, has been considered a possible morphologic marker of mesenchymal cells or cells of mesodermal origin. A retrospective review of human surgical pathology cases studied in a diagnostic electron microscopy laboratory over a five-year period confirmed that SLDs are primarily seen in cells of mesodermal origin in a variety of neoplastic and nonneoplastic tissues. Therefore, SLD may be of value as a mesodermal marker in evaluating poorly differentiated tumors. Furthermore, the presence or absence of SLD in tissue histiocytes in diverse conditions may contribute to the understanding of heterogeneity among this group of cells.
S S Mirra; M L Miles
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  13     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-07-22     Completed Date:  1982-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  365-80     Citation Subset:  IM    
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MeSH Terms
Carcinoma / ultrastructure
Cell Membrane / ultrastructure*
Fibroma / ultrastructure
Fibrosarcoma / ultrastructure
Granuloma / pathology
Lipoma / ultrastructure
Mesoderm / ultrastructure
Neoplasms / diagnosis,  ultrastructure*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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