Document Detail

Subpedicle connective tissue graft versus guided tissue regeneration with bioabsorbable membrane in the treatment of human gingival recession defects.
MedLine Citation:
PMID:  9848537     Owner:  NLM     Status:  MEDLINE    
The purpose of the present clinical study was to evaluate the effect of guided tissue regeneration (GTR) in comparison to subpedicle connective tissue graft (SCTG) in the treatment of gingival recession defects. A total of 12 patients, each contributing a pair of Miller's Class I or II buccal gingival recessions, was treated. According to a randomization list, one defect in each patient received a polyglycolide/lactide bioabsorbable membrane, while the paired defect received a SCTG. Treatment effect was evaluated 6 months postsurgery. Clinical recordings included full-mouth and defect-specific oral hygiene standards and gingival health, recession depth (RD), recession width (RW), probing depth (PD), clinical attachment level (CAL), and keratinized tissue width (KT). Mean RD significantly decreased from 3.1 mm presurgery to 1.5 mm at 6 months postsurgery for the GTR group (48% root coverage), and from 3.0 mm to 0.5 mm for the SCTG group (81% root coverage). RD reduction and root coverage were significantly greater in SCTG group compared to GTR group. Mean CAL gain amounted to 1.7 mm for the GTR group, and 2.3 mm in the SCTG group. No significant differences in PD changes were observed within and between groups. KT increased significantly from presurgery for both treatment groups, however gingival augmentation was significantly greater in the SCTG group compared to GTR group. Results indicate that: 1) treatment of human gingival recession defects by means of both GTR and SCTG procedures results in clinically and statistically significant improvement of the soft tissue conditions of the defect; and 2) treatment outcome was significantly better following SCTG compared to GTR in terms of recession depth reduction, root coverage, and keratinized tissue increase.
L Trombelli; A Scabbia; D N Tatakis; G Calura
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of periodontology     Volume:  69     ISSN:  0022-3492     ISO Abbreviation:  J. Periodontol.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-01-27     Completed Date:  1999-01-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1271-7     Citation Subset:  D; IM    
Department of Periodontology, School of Dentistry, University of Ferrara, Italy.
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MeSH Terms
Absorbable Implants*
Biocompatible Materials / therapeutic use
Connective Tissue / transplantation
Gingiva / transplantation*
Gingival Recession / surgery*
Guided Tissue Regeneration, Periodontal* / methods
Lactic Acid / therapeutic use
Membranes, Artificial
Middle Aged
Polymers / therapeutic use
Surgical Flaps
Treatment Outcome
Reg. No./Substance:
0/Biocompatible Materials; 0/Membranes, Artificial; 0/Polymers; 26100-51-6/poly(lactic acid); 50-21-5/Lactic Acid

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