Document Detail


Submicroscopic deletion of chromosome region 16p13.3 in a Japanese patient with Rubinstein-Taybi syndrome.
MedLine Citation:
PMID:  7864045     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a series of 25 Japanese patients with Rubinstein-Taybi syndrome, we screened, by high-resolution GTG banding and fluorescence in situ hybridization of a cosmid probe (RT1, D16S237), for microdeletions associated with this syndrome. In one patient, a microdeletion was demonstrated by in situ hybridization, but none were detected by high-resolution banding.
Authors:
M Masuno; K Imaizumi; K Kurosawa; Y Makita; F Petrij; H G Dauwerse; M H Breuning; Y Kuroki
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of medical genetics     Volume:  53     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-03-22     Completed Date:  1995-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  352-4     Citation Subset:  IM    
Affiliation:
Division of Medical Genetics, Kanagawa Children's Medical Center, Yokohama, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cheek
Child
Child, Preschool
Chromosome Deletion*
Chromosomes, Human, Pair 16*
Cytogenetics / methods
Female
Humans
In Situ Hybridization, Fluorescence
Infant
Japan / epidemiology
Male
Mouth Mucosa*
Pregnancy
Rubinstein-Taybi Syndrome / epidemiology,  genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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