Document Detail

Sublingual versus oral misoprostol for uterine evacuation following early pregnancy failure.
MedLine Citation:
PMID:  19426973     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the efficacy of misoprostol administered sublingually or orally for uterine evacuation after early pregnancy failure. METHOD: Forty-eight hours after receiving 200 mg of mifepristone orally, 100 women were randomized to receive misoprostol sublingually or orally. RESULTS: The evacuation rates were 92% in the sublingual and 84% in the oral administration group; the mean+/-SD induction-to-evacuation intervals were 5.6+/-4.54 hours and 9.44+/-5.61 hours, this difference being significant; and the adverse effects were similar in the 2 groups. CONCLUSION: The sublingual route was found to be as effective but faster than the oral route for uterine evacuation after early pregnancy failure.
Beenu Kushwah; Abha Singh
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-05-07
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  106     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-08     Completed Date:  2009-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  43-5     Citation Subset:  IM    
Lady Harding Medical College, Delhi, India.
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MeSH Terms
Abortifacient Agents, Nonsteroidal / administration & dosage,  adverse effects,  therapeutic use*
Abortion, Incomplete / drug therapy*
Administration, Oral
Administration, Sublingual
Misoprostol / administration & dosage,  adverse effects,  therapeutic use*
Time Factors
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

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