Document Detail

Sublethal effects of phenol on the phospholipid fatty acid composition of carp erythrocyte plasma membrane.
MedLine Citation:
PMID:  9931236     Owner:  NLM     Status:  MEDLINE    
The effect of different concentrations (5, 10, and 20 ppm) of phenol on the carp erythrocyte plasma membrane was examined following exposures of 48 and 96 h. The results indicated that the high concentrations of phenol pollutant led to an increase in phosphatidylcholine (PC) and eliminated phosphatidylinositol (PI), phosphatidylserine (PS), and phosphatidic acid (PA). The data also revealed that arachidonic acid (20:4 n-6) was present in the greatest amounts; its quantity in both low and high doses increased throughout the experimental period. The n-3 fatty acids (eicosapentaenoic, 20:5 n-3, and docosahexaenoic acids, 22:6 n-3) displayed a fairly varied picture after exposure to phenol pollutant. Long-term exposure to higher phenol concentrations led to elimination of these acids and significantly decreased n-3/n-6 ratios.
H M Kotkat; A A Rady; N Janos
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  42     ISSN:  0147-6513     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-03-03     Completed Date:  1999-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  35-9     Citation Subset:  IM    
Copyright Information:
Copyright 1999 Academic Press.
Department of Biochemistry, Attila Jozsef University, Szeged, Hungary.
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MeSH Terms
Erythrocyte Membrane / drug effects*,  metabolism
Fatty Acids / metabolism*
Phenol / toxicity*
Phospholipids / metabolism*
Water Pollutants, Chemical / toxicity*
Reg. No./Substance:
0/Fatty Acids; 0/Phospholipids; 0/Water Pollutants, Chemical; 108-95-2/Phenol

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