Document Detail


Subjective sleep duration and quality influence diet composition and circulating adipocytokines and ghrelin levels in teen-age girls.
MedLine Citation:
PMID:  20733266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Understanding the interplay between sleep duration and quality, diet and hormones of obesity may help design effective lifestyle intervention strategies. Here we studied such associations in lean and obese teen-aged Saudi girls. In this cross-sectional observational study, 126 girls (62 lean and 64 obese) aged 14 -18 years (16.5 ± 1.5) were evaluated. A general questionnaire, which included sleep and diet questions, was obtained and anthropometric measurements and overnight fasting blood samples for determination of glucose, lipid profile and serum levels of leptin, adiponectin, resistin and ghrelin were collected. Subjects that slept < 5 hours/day had a higher percent of carbohydrate intake (p = 0.04) than those who slept > 7 hours/day. Adiponectin levels were higher in the lean than the obese group and increased in proportion to hours of sleep. Ghrelin had an inverse association with subjective sleep duration (p = 0.04), while resistin levels were directly proportional to it. Thus, the duration and quality of sleep influenced diet composition and the circulating levels of adipocytokines and ghrelin in adolescent girls. Long and uninterrupted sleep was associated with a better diet and a more favorable hormonal profile.
Authors:
Dara Al-Disi; Nasser Al-Daghri; Latifa Khanam; Abdulaziz Al-Othman; Mohammad Al-Saif; Shaun Sabico; George Chrousos
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-21
Journal Detail:
Title:  Endocrine journal     Volume:  57     ISSN:  1348-4540     ISO Abbreviation:  Endocr. J.     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-04     Completed Date:  2011-03-03     Revised Date:  2012-04-09    
Medline Journal Info:
Nlm Unique ID:  9313485     Medline TA:  Endocr J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  915-23     Citation Subset:  IM    
Affiliation:
Department of Community Health Sciences, College of Applied Medical Science, Riyadh, Kingdom of Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adipokines / blood*
Adiponectin / blood
Adolescent
Body Mass Index
Cross-Sectional Studies
Diet*
Energy Intake
Female
Ghrelin / blood*
Humans
Obesity / blood,  physiopathology*,  prevention & control
Questionnaires
Resistin / blood
Saudi Arabia
Sleep*
Chemical
Reg. No./Substance:
0/ADIPOQ protein, human; 0/Adipokines; 0/Adiponectin; 0/Ghrelin; 0/RETN protein, human; 0/Resistin

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