Document Detail


Subincanadines A-C, novel quaternary indole alkaloids from Aspidosperma subincanum.
MedLine Citation:
PMID:  12201766     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three novel quaternary indole alkaloids with an unprecedented 1-azoniatricyclo[4.3.3.0(1,5)]undecane moiety, subincanadines A-C (1-3), as well as two new indole alkaloids with a 1-azabicyclo[5.2.2]undecane moiety, subincanadines D (4) and E (5), and a new indole alkaloid with a 1-azabicyclo[4.3.1]decane moiety, subincanadine F (6), have been isolated from the barks of Aspidosperma subincanum Mart, and the structures of 1-6 and the stereochemistry of 1-3 were elucidated by spectroscopic data and chemical means.
Authors:
Jun'ichi Kobayashi; Mitsuhiro Sekiguchi; Sayaka Shimamoto; Hideyuki Shigemori; Haruaki Ishiyama; Ayumi Ohsaki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  67     ISSN:  0022-3263     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-08-30     Completed Date:  2003-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6449-55     Citation Subset:  IM    
Affiliation:
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. jkobay@pharm.hokudai.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aspidosperma / chemistry*
Brazil
Indole Alkaloids / chemistry,  isolation & purification*
Inhibitory Concentration 50
Molecular Conformation
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Oxidation-Reduction
Plant Bark / chemistry
Plants, Medicinal / chemistry*
Chemical
Reg. No./Substance:
0/Indole Alkaloids; 0/subincanadine A; 0/subincanadine B; 0/subincanadine C

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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