Document Detail

Subgingival Epstein Barr and Cytomegalovirus Occurrence in Pregnancy Gingivitis.
MedLine Citation:
PMID:  21513469     Owner:  NLM     Status:  Publisher    
Background: Although recent studies have focused on the role of human herpes viruses in various types of periodontal disease, there is a lack of information in these reports regarding the role of pregnancy gingivitis. The aim of this study was to determine the correlation between pregnancy and subgingival virus presence and their relationship with the clinical parameters. Methods: Seventy pregnant and 40 non-pregnant women were examined for gingival and plaque indices, bleeding on probing (BOP), and clinical pocket depths (CPD) from whole dentition. Subgingival plaque samples were obtained from sites showing signs of gingivitis as well as from healthy sites. The polymerase chain reaction methodology was used to detect Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) from plaque samples. Results: Our results show that the gingivitis lesions of 27 (38.6%) and 10 (14.3%) of the pregnant subjects were positive for EBV and CMV, respectively. In the non-pregnant group, EBV and CMV were detected in 6 (15%) and 8 (20%) of the lesions, respectively. A statistically significant difference (p<0.01) was found between the subgingival occurrence of EBV in the two groups. In gingivitis sites, CPD was affected by gestation (p<0.001) and by the occurrence of EBV (p<0.001). In healthy sites CPD was affected by gestation (p<0.05) and BOP was affected by the occurrence of CMV and EBV (p<0.001). Conclusion: Our data indicates that pregnancy increased the risk of subgingival EBV presence in pregnant women by 3.647 times more than that of non-pregnant women.
Gülden Ereş; Elif Altıok; Aykut Ozkul; Cengiz Han Açıkel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-29
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-4-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey.
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